Smart Core Control · Unwavering Reliability: The Core Advantages of the Haoran Fermenter
Ultimate cleanliness and full-process aseptic assurance: Haoran products employ an integrated CNC polishing process to deeply treat the internal cavity, achieving an ultra‑high surface finish of Ra ≤ 0.1–0.4 μm (EP grade) on all material‑contact surfaces throughout the vessel. This eliminates microscopic crevices and dead corners where contaminants could accumulate. The vessel head integrates a quick‑release clamp and a triple aseptic sealing system, while critical ports such as the manway, sight glass, and feed inlet are designed to meet hygienic fluid‑handling standards. The system supports in‑situ steam sterilization (SIP) and online cleaning (CIP), enabling seamless closed‑loop operation from media preparation and high‑temperature sterilization to batch discharge.
Precision Environmental Parameter Control Expert:
Precise and efficient oxygen transfer: Equipped with a variable-speed, multi-stage impeller system featuring both flat and inclined blades, it supports two operating modes—cantilever shaft and bottom magnetic levitation shaft—and, paired with an annular jet distributor, enables precise dissolved oxygen (DO) gradient control, maintaining DO saturation deviation within ±0.5 ppm.
Highly stable temperature control: Combines a jacketed coil with an inverter‑controlled cooling medium regulation module, employing a multi‑point thermistor sensing network to maintain temperature fluctuations within ±0.3°C; includes a cryogenic liquid nitrogen nozzle interface to meet the demands of ultra‑low temperature fermentation.
Precise pH Control/Automatic Defoaming: Imported acid metering pumps and peristaltic alkali pumps make precise adjustments based on real-time biosensor data; integrated high-speed laser foam monitoring probes work in tandem with high-pressure defoamer spray valves to eliminate foam interference in real time.
Intelligent Monitoring Module Integration: The equipment is equipped with an IoT edge processing terminal, fully compatible with OPC-UA and Modbus-TCP protocols, enabling dynamic acquisition and analysis of key real-time curves such as DO, temperature, pH, tank pressure, and feed rate. An optional high-definition endoscopic panoramic camera system can be installed to monitor mycelial growth and floc conditions inside the tank, supporting AI-driven prediction of abnormal behaviors. All operational logs can be stored and exported as JSON files for GMP production traceability audits.
Empowering Multiple Industries: Driving the Industrialization of Biotechnology with Precision
Upgrading the Food and Seasoning Brewing Industry:

A major domestic condiment manufacturer uses Haoran’s custom-designed 10‑ton fully automatic yeast propagation tank, achieving a 12% increase in fermentation rate.
Soy sauce producers in the Southwest region have replaced traditional large-tank fermentation with an array of 120 m² fiber-optic bioreactors, shortening the production cycle by 30% and reducing fusel oil formation by 40%.
Breakthrough in the Biopharmaceutical Field:

A certain recombinant protein drug CDMO uses 100-L Haoran bioreactors for high-throughput expansion of the seed bank, increasing the cell density per reactor from OD600 = 120 to OD600 = 240.
Vaccine companies have deployed the Haoran tank cluster with deep microcarrier-based formulation, successfully achieving efficient Vero cell expansion.
A microbial formulation company has successfully addressed the risk of bacteriophage infection in Bacillus by implementing a modular, high-density microencapsulation fermentation system.
Green Manufacturing of Bio-based Materials:

The bio-PHA production project utilizes Haoran’s high-pressure air‑agitated aerobic fermenters (operating pressure ≥ 1.2 MPa), effectively addressing the challenge of insufficient polymer chain extension.
An environmental technology company used Haoran tanks to build an anaerobic ammonium oxidation system for treating landfill leachate, achieving an ammonia-nitrogen removal rate of 98.5% and enabling the resource recovery of industrial wastewater.
Upgrading Agricultural Biofermentation:

Large-scale biofertilizer manufacturers use five parallel Haoran deep-liquid fermentation platforms to propagate live bacteria, increasing the survival rate of probiotics to 10^11 CFU/g.
The high-end organic agriculture park employs a micro-scale plant auxin fermentation system to precisely produce crop biostimulants through fermentation.